CBS Genome Atlas Database
Center for Structural Genomics of Infectious Diseases
CSGID
applies state-of-the-art high-throughput (HTP) structural biology
technologies to experimentally characterize the three dimensional atomic
structure of targeted proteins from pathogens in the NIAID Category A-C
priority lists and organisms causing emerging and re-emerging
infectious diseases. The three dimensional structure of proteins will
assist drug design and development by yielding direct insights into the
target molecular mechanisms, in interaction with other biological
molecules, or with synthetic compounds, in order to improve selectivity,
specificity and optimize drug development in a rational way.
http://www.csgid.org/csgid/
Genome Web by Applied Biosystems
HAPMAP
The
International HapMap Project is a partnership of scientists and funding
agencies from Canada, China, Japan, Nigeria, the United Kingdom and the
United States to develop a public resource that will help researchers
find genes associated with human disease and response to
pharmaceuticals.
The HMMER project is a Howard Hughes Medical Institute visiting project, hosted at HHMI Janelia Farm Research Campus. The project team currently consists of Rob Finn and Jody Clements, who are affiliated to the Scientific Computing department. In collaboration with the Eddy-Rivas laboratory, the aim is to provide state-of-the-art, freely accessible web interfaces and services to allow users to perform rapid sequence analysis using the HMMER3 software suite. The servers should allow HMMER3 to be applied to a wide variety of questions concerning sequence function, conservation and evolution.
http://hmmer.janelia.org/
Human Genome Project Information by the Department of Energy
The Human Genome Sequencing Center (HGSC)
The
Human Genome Sequencing Center (HGSC) was established in 1996 when the
National Human Genome Research Institute (NHGRI) designated Baylor
College of Medicine as one of six pilot programs for the final phases of
the Human Genome Project (HGP). The HGP is now in a new phase of
exploring individual DNA sequence variation and its association with
human diseases. The HGSC is characterizing normal genetic variation in
human populations. The results are anticipated to change the way we
understand disease and other life processes.
https://www.hgsc.bcm.edu/ KEGG: Kyoto Encyclopedia of Genes and Genomes
A
bioinformatics resource named KEGG is part of the research projects of
the Kanehisa Laboratories in the University of Tokyo to nable
computational prediction of higher-level complexity of cellular
processes and organism behaviors from genomic and molecular information.
http://www.genome.ad.jp/kegg/ Rat Genome Database
"The Rat Genome Database (RGD) curates and integrates rat genetic and genomic data and provides access to this data to support research using the rat as a genetic model for the study of human disease".
http://www.rgd.mcw.edu/
UniProt: protein sequence and function
The mission of UniProt is to provide the scientific community with a comprehensive, high-quality and freely accessible resource of protein sequence and functional information. UniProt provides access to the UniProtKB Protein knowledgebase, which consists of two sections, including Swiss-Prot, which is manually annotated and reviewed, and TrEMBL, which is automatically annotated and is not reviewed. UniRef Sequence clusters is used to speed up similarity searches, and UniParc Sequence archive can be used to keep track of sequences and their identifiers. UniProt also provides access to supporting data, literature citations, taxonomy, keywords and more.
http://www.uniprot.org |